In vitro fertilization (IVF) is a medical procedure that helps couples unable to conceive naturally to have a child. IVF involves the fertilization of an egg by sperm in a laboratory setting. The resulting embryo is then transferred to the mother’s womb, where it can implant and develop into a baby. Before implantation, the embryos are tested for the presence of any genetic disorders.
It is crucial to conduct genetic testing as genetic disorders in embryos can lead to miscarriage or unsuccessful implantation. The embryos with defects are rejected, and only healthy embryos are used for implantation. Screening is impactful during IVF as it increases the likelihood of getting pregnant.
IVF cannot completely rule out genetic disorders, but it can help reduce the risk of passing on genetic diseases to offspring. Genetic disorders like sickle cell disease are caused by mutations transferred from parent to child at birth. Another reason for genetic disorders is changes in the number of structures of chromosomes. There are two types of preimplantation genetic testing (PGT) that can be used with IVF:
Both PGD and PGS can be performed during IVF by taking a small sample of cells from an embryo. The cells are then analyzed for genetic abnormalities. If the embryo is found to be free of genetic disorders, it can be transferred to the mother’s womb.
PGT is not without risks. There is a slight chance that the biopsy could damage the embryo or lead to miscarriage. However, the risks of PGT are generally considered to be outweighed by the potential benefits of preventing the birth of a child with a genetic disorder.
PGS is a newer technique than PGD, and more data on its long-term safety must be collected. However, it is generally considered to be a safe procedure.
PGD involves taking a small sample of cells from an embryo created through IVF. The cells are then analyzed for genetic abnormalities. This can be done using various techniques, including fluorescent in situ hybridization (FISH), polymerase chain reaction (PCR), and microarray analysis.
If the embryo is found to have a genetic abnormality, it will not be transferred to the mother’s womb. This helps to prevent the birth of a child with a genetic disorder and promotes healthy pregnancy.
PGS involves taking a small sample of cells from an embryo that has been created through IVF. The cells are then analyzed for chromosomal abnormalities. This can be done using various techniques, including FISH, PCR, and microarray analysis.
If the embryo has a chromosomal abnormality, it is less likely to implant in the mother’s womb or to develop into a healthy baby. PGS can help identify embryos that are more likely to be successful and can increase the chances of a successful IVF pregnancy.
The benefits of PGT include:
The risks of PGT are:
PGT may be a good option for couples who:
IVF cannot completely rule out genetic disorders, but it can help reduce the risk of passing genetic diseases to offspring. PGT is a valuable tool that can help couples to have healthy baby.
PGD and PGS are not required for couples undergoing IVF treatment as it depends on different circumstances. Various factors include unsuccessful IVF cycles, past miscarriages, medical history, a family history of genetic diseases, etc.
If you are considering PGT, it is essential to talk to your doctor about the risks and benefits of the procedure. You should also make sure you choose a clinic with experience performing PGT. Aveya IVF Centre provides you with the best infertility solutions, and our specialized staff helps you conceive with minimal testing and invasiveness.