Vitrification is a flash eggs freezing method that prevents the formation of ice crystals, which can damage the egg, sperm, embryo or ovarian tissue under other conventional freezing techniques.
When eggs are frozen, they are brought from a temperature of 98.6°F (37°C) all the way down to -320°F (-196°C) instantaneously. Vitrification dehydrates the cells prior to egg freezing using protectants to remove as much water as possible (thus preventing harmful ice crystals from forming).
The best egg freezing process, vitrification, has been proven to have a 99% survival rate. In comparison to traditional freezing methods, which have around 55% egg survival rates, flash freezing eggs uses cryoprotectants that help restore the cell to its original form.
Eggs are one of the largest cells in the human body and are comprised of two main parts: the zona pellucida (a glycoprotein envelope) and the ooplasm (the nucleus, containing mitochondria, endoplasmic reticulum, and the Golgi system). Because they are the largest cells in the body, they are particularly susceptible to damage from ice crystal formation.
This breakthrough in fertility preservation allows women seeking reproductive tissue preservation to bank healthy eggs prior to medical treatments that may affect their fertility.
Aveya Fertility Center is a top fertility clinic that has an operational donor egg bank in India using vitrification to freeze eggs.